How to Prime the Body for Optimal Fat Loss
By Mike Hazle, Oct 20, 2021

Mike Hazle’s Angle for Ideal Fat Loss Optimization
This is a very controversial topic. The following is Mike Hazle's interpretation of the data and does not necessarily reflect the opinions of the Keiser Corporation. Mike is a former Team U.S.A. Olympian, National Championship and International Medalist, and U.S. Air Force Special Warfare Combat Controller - he recommends people do their own research to discover what works for their particular situation. Some of these methods can be dangerous if taken to the extreme (i.e., hypothermia from excess cold or negative effects of taking too many EPA’s). It is best to consult your physician or nutritionist when exploring methods of fat loss.
- Sleep – Get good quality sleep. If you have poor sleep quality, your nervous system will be degraded and your entire ability to oxidize fat will be diminished.
- EPA’s – Essential fatty acids supplementation. Strive to consume at least 1,000mg a day of essential fatty acids (fish oils). This can help support your metabolism and condition yourself for optimal fat loss.
- Glutamine supplementation – Give glutamine to the neurons in your gut to help keep sugar cravings down.
- Iodine and Selenium supplementation – These will help to boost thyroid function and efficiency.
- The neurons that favor the fat burning process are best stimulated by adrenaline/norepinephrine. That means you need to move your body, also known as exercise!
- Oxidizing fat is greatly enhanced by “fidgeting” or non-exercise physical activity. Studies have shown that fidgeters burn 800-2500 more calories than those at rest. Try to achieve low level movement all day long.
- Continuous, subtle, low-impact, and low-intensity movement for long periods of time or constantly throughout the day is ideal.
- Shivering or shuddering is an extremely powerful way to increase fat metabolism and fat loss. That means you should GET COLD! Shivering is an involuntary somatic motor response that occurs in skeletal muscles when a chemical known as succinate is released to produce heat during exposure to cold environments. It’s the shivering that initiates the conversion of the white fat to beige fat to brown fat. Don’t resist the shiver! If you don’t shiver in an ice bath, you won’t get the “succinate” release that activates that transition. Cold or ice baths can “turn up the burn”!
- As a rule of thumb, you want to use the minimal amount of stimulus to promote growth or progress. Hence, you should be careful of becoming cold adaptive.
Types of Training and Fat Loss
- Sprint intensity training (SIT) – all out exertion, under 30sec of work.
- High intensity interval training (HIIT) – up to max or 90% max effort for 1-4min of work.
- Moderate intensity (MICT) – continuous for 40-60% max effort for 20-40min of work.
- Fat is not lost through sweat, urine, or stool. FAT IS LOST ONE CARBON ATOM AT A TIME AND ONE BREATH AT A TIME!
Other Ways to Supplement Fat Loss
- Use caffeine safely and moderately - It will stimulate the release of norepinephrine and adrenaline, which are the gate keepers for mobilization and oxidization of fat.
- Try alternative means of ingesting caffeine such as tea leaves. The caffeine in tea leaves increases GLP1 (glucagon pathway) and thus increases fat oxidization. You can even reuse tea leaves to get more of the GLP1 out of the leaves.
- Try supplementation of Acetyl-L-carnitine – Acetyl-L-carnitine is made from L-carnitine in the body. L-carnitine and acetyl-L-carnitine are used to help the body turn fat into energy and helps facilitate the oxidation of fat by converting fatty acids into ATP, or the energy currency!
References:
- Huberman, A. (2021, May 24). How to Lose Fat with Science-Based Tools [Video Podcast]. Huberman Lab Podcast #21.
- Celi, FS. Human Brown Adipose Tissue Plasticity: Hormonal and Environmental Manipulation. 2018 Mar 8. In: Spiegelman B, editor. Hormones, Metabolism and the Benefits of Exercise [Internet]. Cham (CH): Springer; 2017.